U.S. DOD/CDMRP: Peer Reviewed Medical Research Program (PRMRP)

Applications submitted to the FY26 PRMRP must address one or more of the following congressionally mandated topic areas:

Accelerated Aging Processes Associated with Military Service | Angelman Syndrome | Burn Pit Exposure | Brain Injury Impact on Cardiac Health | Celiac Disease | Congenital Cytomegalovirus | Dystonia | Eating Disorders | Eczema | Ehlers-Danlos Syndrome | Endometriosis | Facioscapulohumeral Muscular Dystrophy | Fibrous Dysplasia/McCune-Albright Syndrome | Food Allergies | Fragile X | Frontotemporal Degeneration | Gambling Addiction | Hepatitis B | Hereditary and Acquired Ataxia | Hereditary Hemorrhagic Telangiectasia | Hermansky-Pudlak Syndrome | Hydrocephalus | Hypertrophic Dyschromia | Hypoxia | Infertility Associated with Military Aviators and Aviation Support Personnel | Inflammatory Bowel Disease | Interstitial Cystitis | Intranasal Ketamine Anesthetics | Maternal Mental Health | Mitochondrial Disease | Musculoskeletal Health | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | Myotonic Dystrophy | Orthotics and Prosthetics Outcomes | Pancreatitis | Pediatric Acute-Onset Neuropsychiatric Syndrome and Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus | Peripheral Neuropathy | Polycystic Kidney Disease | Post-Traumatic Stress Disorder | Prader-Willi Syndrome | Proteomics | Pulmonary Fibrosis | Respiratory Health | Rett Syndrome | Sarcoidosis | Scleroderma | Sickle-Cell Disease | Sleep Disorders and Restriction | Spinal Muscular Atrophy | Suicide Prevention | Tuberculosis | von Hippel-Lindau Syndrome

Clinical Trial Award (Preproposal): Supports the rapid execution and analysis of clinical trials with the potential to have a significant impact on the treatment or management of a disease or condition addressed in one of the FY26 PRMRP topic areas and one of the FY26 PRMRP strategic goals.

Funding: up to $20M for 4 years. .

Impact Award (LOI): Supports applied research, defined as use-inspired and practice-oriented science that brings together outcomes from basic research and insights from the real-world environment to foster clinical applicability.

Funding: up to $3.6M for 4 years.

Lifestyle and Applied Health Research Award (LOI): Supports clinical research and/or clinical trials using a combination of scientific disciplines, including occupational science, psychology, psychometrics, biostatistics and epidemiology, surveillance, implementation science, and population health.

Funding: up to $4.2 for 4 years.

Platform Clinical Translation Award (Preproposal): Supports the translational development and/or earlyphase clinical trials for broadly applicable clinical technologies that will address urgent and complex needs related to two FY26 PRMRP topic areas.

Funding: up to $15M for 4 years.

Technology/Therapeutic Development Award (LOI): Supports the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, for a disease or condition related to one of the FY26 PRMRP topic areas and one of the FY26 PRMRP strategic goals.

Funding: $5.6M for 4 years.

https://ebrap.org/eBRAP/public/ProgramFY.htm?programFYId=719111

https://ebrap.org/eBRAP/public/Program.htm