Michael J. Fox foundation: Parkinson’s Disease – Proteoforms Program

The goal of this program is to generate large-scale, high-resolution proteoform datasets across Parkinson’s-relevant brain regions and matched biofluids to enable biomarker discovery and support the development of accessible, clinically meaningful fluid-based biomarkers.

This program supports two complementary funding tracks: 

1. Global Proteoform Profiling: A broad, proteome-wide effort to systematically characterize proteoforms, addressing a critical gap where conventional proteomics fails to capture disease-relevant molecular forms.
2. Tau Proteoform Characterization: A focused track on Parkinson’s-relevant proteoforms of tau, addressing the limited understanding of tau biology in Parkinson’s disease.

Applicants may apply to both tracks but must submit separate applications.

Funding: Up to $1M over 2 years.

Information Sessions: Register online to learn about the program and to ask your questions.

https://forms.cloud.microsoft/r/4UeNwMGVzt

www.michaeljfox.org/funding-opportunities