Breakthrough T1D (formerly JDRF): Establishing immune tolerance in islet cell replacement therapy for type 1 diabetes (T1D) – Competitive LOI’s

To support the development of tolerance induction approaches for islet cell therapy that enables graft-specific immune protection without compromising natural immune defenses. Open to both central and peripheral tolerance induction strategies with prioritization
given to technologies closest to clinical translation.
Funding: up to $900K over 3 years
https://www.breakthrought1d.org/wp-content/uploads/2025/11/RFA_ImmuneTolerance_CallDocument.pdf
https://www.breakthrought1d.org/explore-research/funding-opportunities/