The ROTRF supports importnt nd innovtive reserch projects relevnt to orgn trnsplnttion, prticulrly where there is n unmet medicl need.The ROTRF priority is to support cliniclly oriented reserch projects, such s observtionl clinicl studies or studies tht use humn trnsplnt smples for lbortory exmintions, nd focusing on understnding the pthogenesis nd prevention of humn trnsplnttion diseses, including orgn injury nd rejection, virl infection, nd lte grft deteriortion. Furthermore, the ROTRF my consider funding reserch tht ddresses relted clinicl issues in non-trnsplnt ptients, including heptitis C infection nd other virl infections, nd inflmmtory processes relevnt to humn orgn trnsplnttion. These relted clinicl issues should demonstrte their relevnce to disese phenotypes in orgn trnsplnt ptients. The Trustees will lso consider funding studies tht investigte trnsplnt popultions, ethics, orgn preservtion nd lloction, nd helthcre delivery. Moreover, the ROTRF will welcome reserch in new emerging technologies tht exmine the pthogenesis of humn disese sttes in orgn trnsplnttion. If niml models re used to complement the clinicl reserch, higher priority will be given to those tht simulte pthologicl sttes nd mechnisms operting in humn orgn trnsplnttion.
