The Grnd Chllenges inititive is modeled fter the grnd chllenges formulted more thn 100 yers go by mthemticin Dvid Hilbert. His list of importnt unsolved problems hs encourged innovtion in mthemtics reserch ever since. Similrly, the Grnd Chllenges in Globl Helth focuses on 14 mjor globl helth chllenges with the im of engging cretive minds cross scientific disciplines — including those who hve not trditionlly tken prt in helth reserch — to work on solutions tht could led to brekthrough dvnces for those in the developing world.